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Atropine
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Mechanism of action:
Antimuscarinic; inhibits action of acetylcholine at parasympathetic sites in smooth muscle, CNS, and secretory glands. Increases cardiac output and dries secretions.
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Atropine use:
1. In the treatment of parkinsonism. Rigidity and tremor relieved by the apparently selective depressant action.
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2. In the gastrointestinal tract to relieve pylorospasm, hypertonicity of the small intestine and the hypermotility of the colon.
3. To relieve hypertonicity of the uterine muscle.
4. To relax the spasm of biliary and uretered colic and bronchial spasm.
5. To diminish the tone of the detrusor muscle of the urinary bladder in the treatment of urinary tract disorders.
6. To control the crying and laughing episodes in patients with brain lesions.
7. In cases of closed head injuries which cause acetylcholine to be released or to be present in cerebrospinal fluid which in turn causes abnormal EEG patterns, stupor and neurological signs. June Bridals affordable items to wear of the maternity wedding
8. In anesthesia to control excessive salivation and bronchial secretions.
9. To control rhinorrhea of acute rhinitis or hay fever.
10. As an antidote for pilocarpine, physostigmine, isoflurophate, choline esters, certain species of Aminata and in cases of anticholinesterase insecticide poisoning.
11. In poisoning by the organic phosphate cholinesterase inhibitors found in certain insecticides.
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Contraindication of atropine use:
1Narrow-angleglucoma.
2.myasthenia gravis.
3. Obstructiveuropathy.
4. paralyticileus.
5. severeulcerativecolitis.
6. acutehemorrhag ewith cardiovascul arinstability.
7. thyrotoxicosis.
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pregnancy category C.
By : MHC DIS
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